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orexin antagonist : ウィキペディア英語版
orexin antagonist
An orexin antagonist is a drug that inhibits the effect of orexin by acting as a receptor antagonist of the orexin receptor. Potential applications include treatment of sleep disorders such as insomnia.
== Examples ==

* Almorexant, development of the drug was abandoned in January 2011
* Lemborexant
* SB-334,867, has been shown to produce sedative and anorectic effects in animals,
* SB-408,124
* SB-649,868, in development for potential use in sleep disorders
* Suvorexant, approved for use in sleep disorders under the brand name Belsomra
* TCS-OX2-29, OX2 selective
* RTIOX-276, OX1 selective

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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